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Patients with myocardial infarction should be more careful of thrombosis

Anticoagulants have been used for a long time. Unfractionated heparin was mainly used in the past, but it is easy to cause bleeding, so it is necessary to closely monitor the coagulation function. Low molecular weight heparin has more advantages, easy to use, and can further reduce mortality.

Beijing reader Mr. Li asked: my father was hospitalized for acute myocardial infarction. The doctor told us about many therapeutic drugs, including thrombolytic drugs, anticoagulants and antiplatelet drugs. What are the effects of these drugs?

Expert answer: to understand this problem, we must first know what is thrombosis. There is a layer of membrane inside the blood vessel wall. Once it is damaged, coagulation factors will be absorbed and platelets will be collected to form a large blood clot. This large blood clot is thrombosis. Thrombosis in the brain causes hemiplegia, and thrombosis in the heart causes myocardial infarction. If the blood vessel is completely blocked, the clot needs to be dissolved first. This kind of drug is called thrombolytic drug.

Patients with thrombosis have a high risk of reoccurrence, so it is very important to take precautions. The vast majority of patients have to take antithrombotic therapy for life. This kind of drugs is called 'antithrombotic drugs'. According to the different targets of drugs, they are divided into antiplatelet drugs and anticoagulants. Thrombosis mainly includes two parts: platelets and coagulation factors. Drugs for platelets are called 'antiplatelet drugs', including aspirin, clopidogrel, etc.; drugs for coagulation factors are called' anticoagulants', including heparin, etc.

Anticoagulants have been used for a long time. Unfractionated heparin was mainly used in the past, but it is easy to cause bleeding, so it is necessary to closely monitor the coagulation function. Low molecular weight heparin has more advantages, easy to use, and can further reduce mortality.